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Lavado García, Jesús María
Cuidados materno-infantiles, Envejecimiento y fragilidad, Nuevas tecnologías, Procesos crónicos.
  • Universidad de Extremadura
Hormonal relationships to bone mass in elderly Spanish men as influenced by dietary calcium and vitamin D.
Artículo
05/12/13
Área:
Envejecimiento y fragilidad
Ámbito:
Atención Primaria/Comunitaria
Metodología:
Cohortes
Población:
Mayores (Ancianos) > 65 años
Autores:
Moran JM,Lopez-Arza LG,Lavado-Garcia JM,Pedrera-Canal M,Rey-Sanchez P,Rodriguez-Velasco FJ,Fernandez P,Pedrera-Zamorano JD
Ref. Bibliográfica:
Moran JM, Lopez-Arza LG, Lavado-Garcia JM, Pedrera-Canal M, Rey-Sanchez P, Rodriguez-Velasco FJ, Fernandez P, Pedrera-Zamorano JD. Hormonal relationships to bone mass in elderly Spanish men as influenced by dietary calcium and vitamin D. Nutrients. 2013 Dec 4;5(12):4924-37.

We aim to evaluate whether calcium and vitamin D intake is associated with 25-hydroxyvitamin D (25-OH-Vitamin D3) and parathyroid hormone (PTH) serum concentrations or is associated with either the phalangeal dual energy X-ray absorptiometry (pDXA) or the quantitative bone ultrasound (QUS) in independent elderly men. Serum PTH and 25-OH-Vitamin D3 were measured in 195 healthy elderly men (mean age: 73.31 ± 5.10 year). Food intake was quantified using a dietetic scale. Participants with 25-OH-Vitamin D3 levels ≥ 30 ng/mL (75 nmol/L) and a calcium intake of 800-1200 mg/day exhibited the lowest PTH levels (41.49 ± 16.72 ng/mL). The highest PTH levels (75.60 ± 14.16 ng/mL) were observed in the <30 ng/mL group 25-OH-Vitamin D3 with a calcium intake >1200 mg/day. No significant differences in the serum PTH levels based on the serum 25-OH-Vitamin D3 levels were observed among participants with a calcium intake of 800-1200 mg/day. Serum PTH was inversely correlated with serum 25-OH-Vitamin D3 in the entire patient sample (r = -0.288, p = 0.019). No differences in any of the three densitometry techniques were observed between any of the age groups in the 800-1200 mg/day and >1200 mg/day calcium intake groups. PTH levels correlate negatively with serum 25-OH-Vitamin D3 levels, and neither calcium nor vitamin D intake exert a strong influence on either of the two parameters.

Increased bone mineral density is associated with breastfeeding history in premenopausal Spanish women.
Artículo
19/09/13
Área:
Cuidados materno-infantiles
Ámbito:
Atención Primaria/Comunitaria
Metodología:
Estudio descriptivo
Población:
Adultos > 18 años
Autores:
Canal-Macias ML,Roncero-Martin R,Moran JM,Lavado-Garcia JM,Costa-Fernandez Mdel C,Pedrera-Zamorano JD
Ref. Bibliográfica:
Canal-Macias ML, Roncero-Martin R, Moran JM, Lavado-Garcia JM, Costa-Fernandez Mdel C, Pedrera-Zamorano JD. Increased bone mineral density is associated with breastfeeding history in premenopausal Spanish women. Arch Med Sci. 2013 Aug 30;9(4):703-8.

During lactation abundant calcium is lost from the mother as a result of the amount of breast milk produced. Lactation leads to transient fragility, with some women experiencing even fragility fractures, but nearly all of these women subsequently undergo a large increase in bone mineral density (BMD), confirming that the BMD must have declined during lactation but it increases after weaning. We have retrospectively examined the relationship between the duration of breastfeeding and bone properties in Spanish premenopausal healthy women, to identify the site-specific changes in BMD.
Four hundred and thirty-three premenopausal healthy women, 295 with a mean of 7.82 ±6.68 months of exclusive breastfeeding and 138 control women, were studied. We examined total, trabecular and cortical volumetric BMD (mg/mm(3)) at the distal radius using peripheral quantitative computed tomography. Areal BMD (g/cm(2)) was measured using dual energy X-ray absorptiometry at the femoral neck, lumbar spine, trochanter and Ward's triangle. Phalangeal bone ultrasound was measured by amplitude-dependent speed of sound.
Areal BMD analysis at L2-L4 revealed significant intergroup differences (p < 0.05). There were significant intergroup differences in the volumetric BMD in both total and cortical bone (p < 0.05). The observed BMD of breast-feeders was higher than the BMD in non-breast-feeding women. Additionally, the lactation subgroup analysis revealed significant differences in the areal BMD at trochanter and L2-L4 (p < 0.05) and in the cortical volumetric BMD (p < 0.05).
This study adds to the growing evidence that breastfeeding has no deleterious effects and may confer an additional advantage for BMD in premenopausal women.

Bone ultrasound and physical activity in postmenopausal spanish women.
Artículo
16/09/13
Área:
Procesos crónicos
Ámbito:
Atención Primaria/Comunitaria
Metodología:
Experimental
Población:
Adultos > 18 años
Autores:
Calderon-Garcia JF,Lavado-Garcia JM,Martin RR,Moran JM,Canal-Macias ML,Pedrera-Zamorano JD
Ref. Bibliográfica:
Calderon-Garcia JF, Lavado-Garcia JM, Martin RR, Moran JM, Canal-Macias ML, Pedrera-Zamorano JD. Bone ultrasound and physical activity in postmenopausal spanish women. Biol Res Nurs. 2013 Oct;15(4):416-21

We studied the effects of moderate physical activity on bone mass in healthy postmenopausal women as assessed by quantitative bone ultrasound. We enrolled a total of 326 postmenopausal women (60.95 ± 8.51 years old and 13.02 ± 9.52 years since menopause) and categorized them by weekly physical activity in their leisure time (sedentary, moderate, and active). We administered a questionnaire on general health and diet and measured bone density by ultrasound on phalanges II-V in the nondominant hand. We found no significant difference in the amplitude-dependent speed of sound (Ad-SoS; p > .05) between sedentary and active women. We concluded that the changes induced by moderate physical activity on bone mass are minimal in healthy postmenopausal women.

Quantitative ultrasound in Spanish children and young adults with cystic fibrosis.
Artículo
05/06/13
Área:
Cuidados materno-infantiles
Ámbito:
Varios Ámbitos
Metodología:
Experimental
Población:
Infantil (niños) > 1 mes < 12 años
Autores:
Lopez-Rodriguez MJ,Lavado-Garcia JM,Canal-Macias ML,Calderon-Garcia JF,Moran JM,Pedrera-Zamorano JD
Ref. Bibliográfica:
Lopez-Rodriguez MJ, Lavado-Garcia JM, Canal-Macias ML, Calderon-Garcia JF, Moran JM, Pedrera-Zamorano JD. Quantitative ultrasound in Spanish children and young adults with cystic fibrosis. Biol Res Nurs. 2013 Jul;15(3):280-4

We studied the relationship between bone density and cystic fibrosis in Spanish children and young adults. We measured the phalangeal bone amplitude-dependent speed of sound (Ad-SoS) in 35 patients with cystic fibrosis and in 30 healthy controls matched for gender, age, and body mass index (BMI). Participants were subjects with normal levels of 25(OH) Vitamin D. We found no difference in Ad-SoS between patients and controls. The only difference between the groups was that the patients had a significantly higher daily caloric intake than the controls (p < .05) as a result of the patient group's greater intake of fats (p < .05). There was a positive correlation between Ad-SoS and weight (p < .0001), but after adjusting for potential confounding factors such as age, the correlation was lost. The percentage of ideal weight did not differ between the two groups. We conclude that well-nourished CF patients had similar Ad-SoS to controls.

Comment on Sanfélix-Genovés et al.: Prevalence of osteoporotic fracture risk factors and antiosteoporotic treatments in the Valencia region, Spain. The baseline characteristics of the ESOSVAL cohort.
Artículo
03/06/13
Área:
Envejecimiento y fragilidad
Ámbito:
Atención Primaria/Comunitaria
Metodología:
Estudio descriptivo
Población:
Mayores (Ancianos) > 65 años
Autores:
Pedrera-Zamorano JD,Lavado-Garcia JM,Moran JM
Ref. Bibliográfica:
Pedrera-Zamorano JD, Lavado-Garcia JM, Moran JM. Comment on Sanfélix-Genovés et al.: Prevalence of osteoporotic fracture risk factors and antiosteoporotic treatments in the Valencia region, Spain. The baseline characteristics of the ESOSVAL cohort. Osteoporos Int. 2013 Jun;24(6):1923-4.

Quantitative bone ultrasound in pediatric patients with cystic fibrosis.
Artículo
11/12/12
Área:
Cuidados materno-infantiles
Ámbito:
Atención Primaria/Comunitaria
Metodología:
Estudio descriptivo
Población:
Infantil (niños) > 1 mes < 12 años
Autores:
Pedrera-Zamorano JD,Lavado-Garcia JM,Moran JM
Ref. Bibliográfica:
Pedrera-Zamorano JD, Lavado-Garcia JM, Moran JM. Quantitative bone ultrasound in pediatric patients with cystic fibrosis. J Cyst Fibros. 2013 Jan;12(1):90.

The protective effect of calcium on bone mass in postmenopausal women with high selenium intake.
Artículo
07/11/12
Área:
Envejecimiento y fragilidad
Ámbito:
Varios Ámbitos
Metodología:
Estudio descriptivo
Población:
Adultos > 18 años
Autores:
Pedrera-Zamorano JD,Calderon-García JF,Roncero-Martin R,Mañas-Nuñez P,Moran JM,Lavado-Garcia JM
Ref. Bibliográfica:
Pedrera-Zamorano JD, Calderon-García JF, Roncero-Martin R, Mañas-Nuñez P, Moran JM, Lavado-Garcia JM. The protective effect of calcium on bone mass in postmenopausal women with high selenium intake. J Nutr Health Aging. 2012;16(9):743-8.

Nutritional factors, especially the two essential nutrients calcium and vitamin D, have been shown to play an important role in bone health. We wanted to determine the possible protective effect of calcium intake in adequate amounts on bone mass as assessed by quantitative ultrasound in postmenopausal women who also have a high intake of selenium.
Health district of Cáceres, Spain. PARTICIPANTS AND STUDY DESIGN: 335 postmenopausal women aged 60.9 (SD = 8.1) years. Women were stratified based on the vitamin D, vitamin E, calcium intake and the calcium/protein and calcium/phosphorous index.
Bone status (Ad-SoS measured at the phalanges) was assessed with an ultrasound device model DBM Sonic 1200R. Food intake was quantified using dietetic scales, measuring cups, and spoons based on 7 days of diet records. Urine samples were collected the morning of testing after an overnight fast. Venous blood samples for the hematological and biochemical studies were also obtained in the fasting state.
In the group of women with Ca intake < 800 mg / d we found a significant and negative relationship between Ad-SoS with age (β= -4.020, F = 23.327) and selenium intake (β = -0.419, F = 10.067), as well as a positive relationship with Ca intake (β= 0.104 and F = 7.084) (p <0.0001 in all). In the group of women with Ca intake > 800 mg / d, age has a significant and negative relationship (β = -4.829 and F = 106.745), whereas folic acid intake has a significant and positive relationship (β = 0.047 and F = 5.858) (p <0.0001 in both).
Elevated selenium intake negatively affects bone mass measurements in postmenopausal women over the age of 51 but only if calcium intake is also less than 800 mg / day. When calcium intake is greater than 800 mg/day, selenium did not appear to affect bone mass.

[Evaluation of the instrumental activities of daily living following a stroke by means of the Lawton and Brody scale].
Artículo
13/09/12
Área:
Procesos crónicos
Ámbito:
Atención Hospitalaria
Metodología:
Validación de instrumentos
Población:
Mayores (Ancianos) > 65 años
Autores:
Jiménez-Caballero PE,López-Espuela F,Portilla-Cuenca JC,Pedrera-Zamorano JD,Jiménez-Gracia MA,Lavado-García JM,Casado-Naranjo I
Ref. Bibliográfica:
Jiménez-Caballero PE, López-Espuela F, Portilla-Cuenca JC, Pedrera-Zamorano JD, Jiménez-Gracia MA, Lavado-García JM, Casado-Naranjo I. [Evaluation of the instrumental activities of daily living following a stroke by means of the Lawton and Brody scale]. Rev Neurol. 2012 Sep 16;55(6):337-42.

The instrumental activities of daily living are activities that are somewhat more complex than basic activities of daily living, and being able to perform them allows a person to be independent within a community. They include housework, tasks involving mobility, managing the home and property; catching the bus; cooking meals and going shopping, among other things.
To evaluate these activities using the Lawton and Brody scale following an ischaemic stroke or intraparenchymatous haemorrhage and to analyse the factors that have an influence on the functional status at six months.
We conducted a prospective study of patients admitted to the stroke unit between September 2010 and June 2011 diagnosed with ischaemic strokes and spontaneous intraparenchymatous haemorrhages. A series of clinical and demographic variables were collected. In the follow-up visit at six months, the patients were re-evaluated by measuring their score on the Lawton and Brody scale again.
The percentages of the Lawton and Brody scale at six months were as follows: 28.9% of patients were highly dependent, 45.4% were moderately dependent and 25.6% were dependent. There were differences according to age, severity and the type of stroke, and also depending on the presence of aphasia or hemiparesis.
Patients who have suffered an ischaemic stroke or haemorrhage present a poorer score in instrumental activities of daily living when age is more advanced, the stroke is more severe and when aphasia or hemiparesis are present.

Bone mass of Spanish school children: impact of anthropometric, dietary and body composition factors.
Artículo
12/03/12
Área:
Cuidados materno-infantiles
Ámbito:
Atención Primaria/Comunitaria
Metodología:
Experimental
Población:
Infantil (niños) > 1 mes < 12 años
Autores:
Lavado-Garcia JM,Calderon-Garcia JF,Moran JM,Canal-Macias ML,Rodriguez-Dominguez T,Pedrera-Zamorano JD
Ref. Bibliográfica:
Lavado-Garcia JM, Calderon-Garcia JF, Moran JM, Canal-Macias ML, Rodriguez-Dominguez T, Pedrera-Zamorano JD. Bone mass of Spanish school children: impact of anthropometric, dietary and body composition factors. J Bone Miner Metab. 2012 Mar;30(2):193-201.

The purpose of this study was to: (a) determine the relationship between quantitative ultrasound (QUS) results and anthropometric, dietary and body composition factors and establish reference ranges for amplitude-dependent speed of sound (Ad-SoS) in the phalanges and broadband ultrasound attenuation (BUA) in the calcaneus of children from Extremadura, Spain, and (b) to present reference curves for this population. Healthy children (n = 245), aged 4-16 years, were included (124 girls and 121 boys). Phalangeal and calcaneal QUS measurements were performed using DBM Sonic Bone Profiler and McCue CUBA Clinical ultrasound devices, respectively. Weight, height and body mass index (BMI) were evaluated by anthropometric methods. Fat percentage, fat mass, lean mass (FFM) and total body water (TBWater) were evaluated by bioelectrical impedance measurements using a Holtain body composition analyzer. Food intake was evaluated by a 7-day food record. A gender analysis revealed that Ad-SoS and BUA parameters increased significantly with age and that both positively correlated with age, weight, height, BMI, FFM and TBWater. For both genders, Ad-SoS showed significant and positive correlations with age, weight, height, BMI, FFM, BUA and TBWater.

Methods for nurses to measure body composition.
Artículo
30/08/11
Área:
Nuevas tecnologías
Ámbito:
Atención Hospitalaria
Metodología:
Validación de instrumentos
Población:
Adultos > 18 años
Autores:
Moran JM,Lavado-Garcia JM,Pedrera-Zamorano JD
Ref. Bibliográfica:
Moran JM, Lavado-Garcia JM, Pedrera-Zamorano JD. Methods for nurses to measure body composition. Rev Lat Am Enfermagem. 2011 Jul-Aug;19(4):1033-8.

Among the methods available for assessing body composition, traditional methods like hydrodensitometry and skin-fold measurements are well known. In this review, we focus on the impedance and interactance methods, which use systems that are usually inexpensive, easily transportable and simple to operate. We also discuss the usefulness of dual energy X-ray absorptiometry, particularly for the measurement of fat distribution. Nurses need to be skilled in the use of the equipment and familiar with the techniques.

ULTRASONIDO ÓSEO DE FALANGES Y SU CORRELACIÓN CON LA DENSITOMETRÍA POR ABSORCIOMETRÍA DE RAYOS X DE DOBLE ENERGÍA PARA EL DIAGNÓSTICO DE OSTEOPENIA/OSTEOPOROSIS EN NUESTRO MEDIO
Tesis
16/01/09 Cáceres
Área:
Nuevas tecnologías
Ámbito:
Varios Ámbitos
Metodología:
Cohortes
Población:
Adultos > 18 años
Universidad:
EXTREMADURA
Año de lectura:
2009

La osteoporosis es una enfermedad sistémica del esqueleto caracterizada por una baja densidad mineral y por el deterioro de la microarquitectura del tejido óseo, con un aumento consecuente en la fragilidad del hueso y la susceptibilidad de sufrir fractura. Las fracturas relacionadas con la osteoporosis causan una morbilidad y mortalidad significativas y están asociadas a una gran carga socioeconómica a nivel mundial.
El objetivo planteado ha sido establecer la relación entre la densitometría por absorciometría de rayos X de doble energía (DXA) y el ultrasonido óseo cuantitativo (QUS) de falanges para valorar calidad y cantidad de hueso, lo que nos permitirá aproximarnos al diagnóstico de osteopenia/osteoporosis, seleccionar pacientes afectos de osteoporosis y proponer las medidas preventivas y/o terapéuticas adecuadas.
Se ha estudiado un total de 2231 mujeres de la Comunidad Autónoma de Extremadura (54.01±10.57 años). A todos los sujetos se les realizó una historia clínica completa, y un cuestionario que incluía factores antropométricos y biológicos, hábitos y estilos de vida, así como enfermedades y tratamientos farmacológicos. Para valorar su masa ósea a todas las mujeres se les realizó una densitometría mediante DXA de columna y cadera (que han permitido el diagnóstico de osteoporosis según criterios de la Organización Mundial de la Salud) y QUS de falanges.
La elevada correlación encontrada entre las técnicas DEXA y QUS nos ha permitido establecer, en las mujeres estudiadas, los valores medios de la velocidad de transmisión del ultrasonido que se corresponden con el diagnóstico de osteopenia, osteoporosis y normalidad según técnica DXA, lo que nos permite hacer una aproximación muy precisa al diagnóstico de osteopenia/ osteoporosis con una técnica sencilla, económica y libre de radiaciones.